The BREATHE Initiative

Asthma affects more than 25 million people in the United States and 339 million people around the world.1,2, it is in fact a heterogeneous disease with varying levels of burden.3 Severe asthma affects approximately 5% to 10% of patients with asthma.4 In these patients it is especially crucial for clinicians to be aware of the importance of having an effective asthma action plan and to recognize the importance of implementing best practices for severe asthma control.

To effectively manage severe asthma, clinicians must appreciate the clinical phenotypes associated with severe asthma, the specific molecular pathways involved in severe asthma, and the integration of molecularly targeted biological therapies for effective and safe patient management. Through an appreciation of the heterogeneity of severe asthma and the properties of specific therapies for the management of severe asthma, clinicians can implement up-to-date strategies to optimize patient care and educate patients. This site serves to provide clinicians with information to help personalize the care of patients with severe asthma and to help clinicians find ways for patients to navigate the dynamic field of personalized care for severe asthma.